{"id":7473,"date":"2023-03-06T15:49:40","date_gmt":"2023-03-06T14:49:40","guid":{"rendered":"https:\/\/professional.vvardis.com\/?page_id=7473"},"modified":"2025-12-12T22:10:19","modified_gmt":"2025-12-12T21:10:19","slug":"letteratura","status":"publish","type":"page","link":"https:\/\/professional.vvardis.com\/it\/letteratura\/","title":{"rendered":"Letteratura"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7473\" class=\"elementor elementor-7473 elementor-7051\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d856f5c elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-id=\"d856f5c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-9b8d604\" data-id=\"9b8d604\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-073c208 elementor-widget elementor-widget-heading\" data-id=\"073c208\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Letteratura<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ae9cda6\" data-id=\"ae9cda6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-238a932 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"238a932\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-879440c\" data-id=\"879440c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1e21a46 elementor-toc--minimized-on-tablet elementor-widget elementor-widget-table-of-contents\" data-id=\"1e21a46\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;exclude_headings_by_selector&quot;:[],&quot;marker_view&quot;:&quot;bullets&quot;,&quot;icon&quot;:{&quot;value&quot;:&quot;&quot;,&quot;library&quot;:&quot;&quot;},&quot;no_headings_message&quot;:&quot;Non sono state trovate intestazioni in questa pagina.&quot;,&quot;headings_by_tags&quot;:[&quot;h2&quot;,&quot;h3&quot;,&quot;h4&quot;,&quot;h5&quot;,&quot;h6&quot;],&quot;minimize_box&quot;:&quot;yes&quot;,&quot;minimized_on&quot;:&quot;tablet&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet_extra&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t\t\t\t<h4 class=\"elementor-toc__header-title\">\n\t\t\t\tTable of Contents\t\t\t<\/h4>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--expand\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__1e21a46\" aria-expanded=\"true\" aria-label=\"Apri l&#039;indice dei contenuti\"><i aria-hidden=\"true\" class=\"fas fa-chevron-down\"><\/i><\/div>\n\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--collapse\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__1e21a46\" aria-expanded=\"true\" aria-label=\"Chiudi l&#039;indice dei contenuti\"><i aria-hidden=\"true\" class=\"fas fa-chevron-up\"><\/i><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<div id=\"elementor-toc__1e21a46\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<i class=\"elementor-toc__spinner eicon-animation-spin eicon-loading\" aria-hidden=\"true\"><\/i>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-990cfdb literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"990cfdb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-87ec418\" data-id=\"87ec418\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d8409f8 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"d8409f8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a3b0a4 elementor-widget elementor-widget-heading\" data-id=\"7a3b0a4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">CURODONT\u2122 REPAIR<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75490ba elementor-widget elementor-widget-heading\" data-id=\"75490ba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">(A) Reviews<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c32cc39 elementor-widget elementor-widget-text-editor\" data-id=\"c32cc39\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol>\n<li>Keeper JH et al. Systematic review and meta-analysis on the effect of self-assembling peptide P11-4 on arrest, cavitation, and progression of initial caries lesions. J Am Dent Assoc. 2023 Jul;154(7):580-591.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37245138\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37245138\/<\/a><\/li>\n<li>Alkilzy M, et al. Biomimetic Enamel Regeneration Using Self-Assembling Peptide P11-4. Biomimetics (Basel). 2023 Jul 4;8(3):290.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37504178\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37504178\/<\/a><\/li>\n<li>B K A, R Y, Puranik MP. Remineralization of early enamel caries lesions using self-assembling peptides P11-4: Systematic review and meta-analysis. J Oral Biol Craniofac Res. 2022 May-Jun;12(3):324-331.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35433245\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35433245\/<\/a><\/li>\n<li>Dawasaz AA, et al. Effectiveness of Self-Assembling Peptide (P11-4) in Dental Hard Tissue Conditions: A Comprehensive Review. Polymers (Basel). 2022 Feb 18;14(4):792.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35215706\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35215706\/<\/a><\/li>\n<li>Mohamed RN, et al. Self-assembling peptide P11-4 in remineralization of enamel caries &#8211; a systematic review of in-vitro studies. Acta Odontol Scand. 2021 Mar;79(2):139-146.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33026894\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33026894\/<\/a><\/li>\n<li>Arifa MK, et al. Recent Advances in Dental Hard Tissue Remineralization: A Review of Literature. Int J Clin Pediatr Dent. 2019 Mar-Apr;12(2):139-144.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31571787\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31571787\/<\/a><\/li>\n<li>Pandya M, Diekwisch TGH. Enamel biomimetics-fiction or future of dentistry. Int J Oral Sci. 2019 Jan 5;11(1):8.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30610185\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30610185\/<\/a><\/li>\n<li>Philip N. State of the Art Enamel Remineralization Systems: The Next Frontier in Caries Management. Caries Res. 2019;53(3):284-295.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30296788\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30296788\/<\/a><\/li>\n<li>Gonz\u00e1lez-Cabezas C, Fern\u00e1ndez CE. Recent Advances in Remineralization Therapies for Caries Lesions. Adv Dent Res. 2018 Feb;29(1):55-59.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29355426\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29355426\/<\/a><\/li>\n<li>Buzalaf MAR, Pessan JP. New Preventive Approaches Part I: Functional Peptides and Other Therapies to Prevent Tooth Demineralization. Monogr Oral Sci. 2017; 26:88-96.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29050026\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29050026\/<\/a><\/li>\n<li>Amaechi BT. Remineralisation &#8211; the buzzword for early MI caries management. Br Dent J. 2017 Aug 11;223(3):173-182.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28798421\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28798421\/<\/a><\/li>\n<li>Clarkson BH, Exterkate RA. Noninvasive dentistry: a dream or reality? Caries Res. 2015;49 Suppl 1:11-7.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25871414\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25871414\/<\/a><\/li>\n<li>Donovan TE, et al. Annual review of selected scientific literature: report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry. J Prosthet Dent. 2014 Nov;112(5):1038-87.&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25443419\/\" target=\"_blank\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25443419\/<\/a><\/li>\n<\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dea9998 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dea9998\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cba4415\" data-id=\"cba4415\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c201a7a elementor-widget elementor-widget-heading\" data-id=\"c201a7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">(B) Early Caries<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35fcc27 elementor-widget elementor-widget-text-editor\" data-id=\"35fcc27\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Atteya SM, et al. Self-assembling peptide and nano-silver fluoride in remineralizing early enamel carious lesions: randomized controlled clinical trial. BMC Oral Health. 2023 Aug 19;23(1):577. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37598194\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37598194\/<\/a><\/li><li>Shah SV, et al. Framework for fiscal impact analysis of managing initial caries lesions with noninvasive therapies. J Am Dent Assoc. 2023 Oct;154(10):897-909.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37770132\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37770132\/<\/a><\/li><li>Br\u00f6seler F, et al. Randomised clinical trial investigating self-assembling peptide P11-4 in the treatment of early caries. Clin Oral Investig. 2020 Jan;24(1):123-132.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31037343\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31037343\/<\/a><\/li><li>Doberdoli D, et al. Randomized Clinical Trial investigating Self-Assembling Peptide P11-4 for Treatment of Early Occlusal Caries. Sci Rep. 2020 Mar 6;10(1):4195. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32144336\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32144336\/<\/a><\/li><li>Schlee M, et. al. Clinical performance of self-assembling peptide P11 -4 in the treatment of initial proximal carious lesions: A practice-based case series. J Investig Clin Dent. 2018 Feb;9(1) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28868637\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28868637\/<\/a><\/li><li>Brunton PA, et al. Treatment of early caries lesions using biomimetic self-assembling peptides-a clinical safety trial. Br Dent J. 2013\u00a0 Aug;215(4) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23969679\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23969679\/<\/a><\/li><li>Sedlakova Kondelova P, et al. Efficacy of P11-4 for the treatment of initial buccal caries: a randomized clinical trial. Sci Rep. 2020 Nov 9;10(1):20211. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33214593\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33214593\/<\/a><\/li><li>Alkilzy M, et al. Treatment of Carious Lesions Using Self-Assembling Peptides. Adv Dent Res. 2018(29):42-47.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29355413\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29355413\/<\/a><\/li><li>Deyhle H, et al. Mineralization of Early Stage Carious Lesions In Vitro-A Quantitative Approach. Dent J (Basel). 2015 Oct 10;3(4):111-122.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29567931\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29567931\/<\/a><\/li><li>Pitts N. Summary of: Treatment of early caries lesions using biomimetic self-assembling peptides&#8211;a clinical safety trial. Br Dent J. 2013 Aug;215(4):174-5.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23969659\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23969659<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8b22c14 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8b22c14\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7a57479\" data-id=\"7a57479\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4274ed6 elementor-widget elementor-widget-heading\" data-id=\"4274ed6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">(C) Orthodontic White Spot Lesions<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f7b0ec elementor-widget elementor-widget-text-editor\" data-id=\"5f7b0ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Kobeissi R, Badr SB, Osman E. Effectiveness of Self-assembling Peptide P11-4 Compared to Tricalcium Phosphate Fluoride Varnish in Remineralization of White Spot Lesions: A Clinical Randomized Trial. Int J Clin Pediatr Dent. 2020; 13:451-456.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33623327\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33623327\/<\/a><\/li><li>Natchiyar N, et al. Comparison of Remineralizing Agents in the Management of White Spot Lesions In Three- to Five-year-old Children: a Clinical Trial. Pediatr Dent. 2023(45):99-106. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37106544\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37106544\/<\/a><\/li><li>Welk A, et al. Effect of self-assembling peptide P11-4 on orthodontic treatment-induced carious lesions. Sci Rep. 2020(10):6819. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32321955\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32321955\/<\/a><\/li><li>Ghaly YS, et al. Effect of self-assembling peptide and other remineralizing agents on preventing initial enamel lesions around orthodontic brackets: An in vitro comparative study. Int Orthod. 2023 Jun;21(2):100751. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37003059\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37003059\/<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9fee876 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9fee876\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1a669b0\" data-id=\"1a669b0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-591909b elementor-widget elementor-widget-heading\" data-id=\"591909b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">(D) Regenerating\/Remineralizing Properties of P11-4<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6a51fe elementor-widget elementor-widget-text-editor\" data-id=\"b6a51fe\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Alkilzy M, et al. Self-assembling Peptide P11-4 and Fluoride for Regenerating Enamel. J Dent Res. 2018 Feb;97(2):148-154. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28892645\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28892645\/<\/a><\/li><li>Nath SJC, et al. Comparison of the Enamel Remineralisation Potential of Self-Assembling Peptides. Int Dent J. 2024 Apr;74(2):187-194. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37743135\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37743135\/<\/a><\/li><li>Shetty SS, Nekkanti S. Remineralization Potential of a Novel Biomimetic Material (Self-assembling Peptide P11-4) on Early Enamel Caries: An In Vitro Study. J Contemp Dent Pract. 2023 Mar 1;24(3):181-187. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37272130\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37272130\/<\/a><\/li><li>\u00d6zdemir \u015e, et al. Remineralization potential of P11-4 and fluoride on secondary carious primary enamel: A quantitative evaluation using microcomputed tomography. Microsc Res Tech. 2022 Feb;85(2):807-812. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34981866\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34981866\/<\/a><\/li><li>\u00dcst\u00fcn N, Akt\u00f6ren O. Analysis of efficacy of the self-assembling peptide-based remineralization agent on artificial enamel lesions. Microsc Res Tech. 2019 Jul;82(7):1065-1072.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045\/<\/a><\/li><li>Jablonski-Momeni A, et al. Impact of self-assembling peptides in remineralisation of artificial early enamel lesions adjacent to orthodontic brackets. Sci Rep. 2020 Sep 15;10(1):15132. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32934335\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32934335\/<\/a><\/li><li>Jablonski-Momeni A, et al. Efficacy of the self-assembling peptide P11-4 in constructing a remineralization scaffold on artificially-induced enamel lesions on smooth surfaces. J Orofac Orthop. 2014 May;75(3):175-90.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24825830\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24825830\/<\/a><\/li><li>Kamal D, et al. Complementary remineralizing effect of self-assembling peptide (P11-4) with CPP-ACPF or fluoride: An in vitro study. J Clin Exp Dent. 2020 Feb 1;12(2):e161-e168.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32071698\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32071698\/<\/a><\/li><li>\u00dcst\u00fcn N, Akt\u00f6ren O. Analysis of efficacy of the self-assembling peptide-based remineralization agent on artificial enamel lesions. Microsc Res Tech. 2019 Jul;82(7):1065-1072.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4a36923 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4a36923\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-06f788f\" data-id=\"06f788f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3555d8f elementor-widget elementor-widget-heading\" data-id=\"3555d8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">(E) In vitro studies<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-00b1f26 elementor-widget elementor-widget-text-editor\" data-id=\"00b1f26\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Barbosa-Martins LF, et al. Enhancing bond strength on demineralized dentin by pre-treatment with selective remineralising agents. J Mech Behav Biomed Mater. 2018;81:214-221 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29550716\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29550716\/<\/a><\/li><li>Barbosa-Martins LF, et al. Biomimetic Mineralizing Agents Recover the Micro Tensile Bond Strength of Demineralized Dentin. Materials (Basel). 2018; 11:1733\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30223511\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30223511\/<\/a><\/li><li>Deyhle H, et al. Mineralization of Early Stage Carious Lesions In Vitro\u2014A Quantitative Approach. Dent J 2015; 3:111-122 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29567931\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29567931\/<\/a><\/li><li>Jablonski-Momeni A, Heinzel-Gutenbrunner M. Efficacy of the \u201cSelf-assembling peptide P11-4\u201d in the formation of a remineralization scaffold on artificially induced enamel lesions on smooth surfaces. J Orofac Orthop 2014; 75:175-190\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24825830\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24825830\/<\/a><\/li><li>Jablonski-Momeni A, et al. Impact of self-assembling peptides in remineralisation of artificial early enamel lesions adjacent to orthodontic brackets. Sci Rep. 2020; 10:15132 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32934335\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32934335\/<\/a><\/li><li>Kamal D, Hassanein H, Elkassas D, Hamza H. Comparative evaluation of remineralizing efficacy of biomimetic self-assembling peptide on artificially induced enamel lesions: An in vitro study. J Conserv Dent. 2018;21:536-541\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30294117\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30294117\/<\/a><\/li><li>Kamal D, Hassanein et al. Complementary remineralizing effect of self-assembling peptide (P11-4) with CPP-ACPF or fluoride: An in vitro study. J Clin Exp Dent. 2020;12:e161-e168\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32071698\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32071698\/<\/a><\/li><li>Knaup T, Korbmacher-Steiner H, Jablonski-Momeni A. Effect of the caries-protective self-assembling peptide P11-4 on shear bond strength of metal brackets. J Orofac Orthop. 2021;82:329-336. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32876755\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32876755\/<\/a><\/li><li>Kucukyilmaz E, Savas S. Measuring the remineralization potential of different agents with quantitative light-induced fluorescence digital Biluminator. J Appl Biomater Funct Mater. 2017;15:e101-e106 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27647387\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27647387\/<\/a><\/li><li>Moreira KM, et al. Impact of biomineralization on resin\/biomineralized dentin bond longevity in a minimally invasive approach: An \u201cin vitro\u201d 18-month follow-up. Dent Mater. 2021;37:e276-e289.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33608139\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33608139\/<\/a><\/li><li>Nath SJC, Fu Y, et al. A Comparison of the Enamel Remineralisation Potential of Self-Assembling Peptides. Int Dent J. 2024 Apr;74(2):187-194 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37743135\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37743135\/<\/a><\/li><li>\u00d6zdemir \u015e, Taran PK, et al. Remineralization potential of P11-4 and fluoride on secondary carious primary enamel: A quantitative evaluation using microcomputed tomography. Microsc Res Tech. 2022;85:807-812\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34981866\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34981866\/<\/a><\/li><li>Savas S, Kucukyilmaz E, et al. Effects of Remineralization Agents on Artificial Carious Lesions. Pediatr Dent. 2016;38:511-518. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28281957\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28281957\/<\/a><\/li><li>Schmidlin P, Zobrist K, et al. In vitro re-hardening of artificial enamel caries lesions using enamel matrix proteins or self-assembling peptides. J Appl Oral Sci. 2016;24:31-6.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27008255\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27008255\/<\/a><\/li><li>Lena Sezici Y, et al. Comparative evaluation of fluoride varnishes, self-assembling peptide-based remineralization agent, and enamel matrix protein derivative on artificial enamel remineralization in vitro. Prog Orthod. 2021 Jan 25;22(1):4.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33491110\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33491110\/<\/a><\/li><li>Shetty SS, Nekkanti S. Remineralization Potential of a Novel Biomimetic Material (Self-assembling Peptide P11-4) on Early Enamel Caries: An In Vitro Study. J Contemp Dent Pract. 2023;24:181-187. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37272130\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37272130\/<\/a><\/li><li>Silvertown JD, et al. Remineralization of natural early caries lesions in vitro by P11 -4 monitored with photothermal radiometry and luminescence. J Investig Clin Dent. 2017;8(4).\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28052551\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28052551\/<\/a><\/li><li>Sindhura V, Uloopi KS, et al. Evaluation of enamel remineralizing potential of self-assembling peptide P11-4 on artificially induced enamel lesions in vitro. J Indian Soc Pedod Prev Dent. 2018;36:352-356.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30324924\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30324924\/<\/a><\/li><li>Suda S, Takamizawa T, et al. Application of the Self- Assembling Peptide P11-4 for Prevention of Acidic Erosion. Oper Dent. 2018;43:E166-E172.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29513639\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29513639\/<\/a><\/li><li>Takahashi F, Kurokawa H, et al. Ultrasonic assessment of the effects of self-assembling peptide scaffolds on preventing enamel demineralization. Acta Odontol Scand. 2016;74:142-7. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26156830\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/26156830\/<\/a><\/li><li>Tripathi P, Mengi R, et al. Evaluation of Remineralizing Capacity of P11-4, CPP-ACP, Silver Diamine Fluoride, and NovaMin: An In Vitro Study. J Contemp Dent Pract. 2021;22:357-360. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34267003\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34267003\/<\/a><\/li><li>\u00dcst\u00fcn N, Akt\u00f6ren O. Analysis of efficacy of the self-assembling peptide-based remineralization agent on artificial enamel lesions. Microsc Res Tech. 2019;82:1065-1072.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30884045<\/a>\u00a0<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-138db25 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"138db25\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3a09773\" data-id=\"3a09773\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c354f9d elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c354f9d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-13959dd elementor-widget elementor-widget-heading\" data-id=\"13959dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">SELF-ASSEMBLING PEPTIDE TECHNOLOGY<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5beca11 elementor-widget elementor-widget-text-editor\" data-id=\"5beca11\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Aggeli A, et al. Responsive gels formed by the spontaneous self-assembly of peptides into polymeric beta-sheet tapes. Nature. 1997 Mar 20;386(6622):259-62.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9069283\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9069283\/<\/a><\/li><li>Aggeli A, et al. pH as a trigger of peptide beta-sheet self-assembly and reversible switching between nematic and isotropic phases. J Am Chem Soc. 2003 Aug 13;125(32):9619-28.\u00a0 \u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12904028\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12904028\/<\/a><\/li><li>Camassari JR, et al. The Self-assembling peptide P11-4 influences viability and osteogenic differentiation of stem cells of the apical papilla (SCAP). J Dent. 2023 Jul;134: 104551.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37201776\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37201776\/<\/a><\/li><li>Carvalho RG, et al. Self-assembled peptide P11-4 interacts with the type I collagen C-terminal telopeptide domain and calcium ions. Dent Mater. 2023 Aug;39(8):708.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37394390\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37394390\/<\/a><\/li><li>Ara\u00fajo IJS, et al. Self-assembly peptide P11-4 induces mineralization and cell-migration of odontoblast-like cells. J Dent. 2022; 121:104111.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35460865\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35460865\/<\/a><\/li><li>de Souza Ara\u00fajo IJ, et al. Self-assembling peptide-laden electrospun scaffolds for guided mineralized tissue regeneration. Dent Mater. 2022 Nov;38(11):1749-1762. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36180310\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36180310\/<\/a><\/li><li>Bommer C, et al. Efficacy and safety of P11-4 for the treatment of periodontal defects in dogs. Clin Oral Investig. 2022 Mar;26(3):3151-3166.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35006293\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35006293\/<\/a><\/li><li>Gharaei R, et al. Biomimetic peptide enriched nonwoven scaffolds promote calcium phosphate mineralisation. RSC Adv. 2020 Jul 29;10(47):28332-28342.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35519117\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35519117\/<\/a><\/li><li>Koch F, et al. Development and application of a 3D periodontal in vitro model for the evaluation of fibrillar biomaterials. BMC Oral Health. 2020; 20:148. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32429904\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32429904\/<\/a><\/li><li>Koch F, et al. A Versatile Biocompatible Antibiotic Delivery System Based on Self-Assembling Peptides with Antimicrobial and Regenerative Potential. Adv Healthc Mater. 2019Jul;8(13): e1900167 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30985084\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30985084\/<\/a><\/li><li>de Sousa JP, et al. The Self-Assembling Peptide P11-4 Prevents Collagen Proteolysis in Dentin. J Dent Res. 2019 Mar;98(3):347-354. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30612505\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30612505\/<\/a><\/li><li>Koch F, et al. Mechanical characteristics of beta sheet-forming peptide hydrogels are dependent on peptide sequence, concentration and buffer composition. R Soc Open Sci. 2018; 5:171562.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29657766\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29657766\/<\/a><\/li><li>Kind L, et al. Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide. J Dent Res. 2017 Jul;96(7):790-797.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28346861\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28346861\/<\/a><\/li><li>Kyle S, Aggeli A, Ingham E, McPherson MJ. Recombinant self-assembling peptides as biomaterials for tissue engineering. Biomaterials 2010;31:9395\u20139405.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20932572\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20932572\/<\/a><\/li><li>Saha S, Yang XB, et al. A biomimetic self-assembling peptide promotes bone regeneration in vivo: A rat cranial defect study. Bone. 2019 Oct; 127:602-611.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31351196\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31351196\/<\/a><\/li><li>Maude S, Ingham E, Aggeli A. Biomimetic self-assembling peptides as scaffolds for soft tissue engineering. Nanomedicine (Lond). 2013 May;8(5):823-47.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23656267\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23656267\/<\/a><\/li><li>Kirkham J, Firth A, et al. Self-assembling peptide scaffolds promote enamel remineralization. J Dent Res. 2007 May;86(5):426-30.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17452562\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17452562\/<\/a><\/li><li>Firth A, Aggeli A, et al. Biomimetic self-assembling peptides as injectable scaffolds for hard tissue engineering. Nanomedicine (Lond). 2006 Aug;1(2):189-99.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17716108\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17716108\/<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-df7cc43 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"df7cc43\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cb6e041\" data-id=\"cb6e041\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0beb8a3 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"0beb8a3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-868f2e8 elementor-widget elementor-widget-heading\" data-id=\"868f2e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">CURODONT PROTECT &amp; CURODONT D\u2019SENZ<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-16434f3 elementor-widget elementor-widget-text-editor\" data-id=\"16434f3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Baltaci E, Bilmenoglu C, et al. Effect of three different remineralising agents on prevention against acidic erosion of primary teeth: an in vitro study. Eur Arch Paediatr Dent. 2023 Oct;24(5):651-659.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37646903\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37646903\/<\/a><\/li><li>Bilge K, K\u0131l\u0131\u00e7 V. Effects of different remineralizing agents on color stability and surface characteristics of the teeth following vital bleaching. Microsc Res Tech. 2021 Oct;84(10):2206-2218.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33852758\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33852758\/<\/a><\/li><li>Gayas Z, Azher U, et al. Comparative Evaluation of Antimicrobial Efficacy of Fluoride-Based and Self-Assembling Peptide P11-4-based Tooth Remineralization Agents on Streptococcus mutans: A Microbiological Study. Contemp Clin Dent. 2023 Apr-Jun;14(2):141-144.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37547429\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37547429\/<\/a><\/li><li>Ghaly YS, El-Wassefy NA, et al. Effect of self-assembling peptide and other remineralizing agents on preventing initial enamel lesions around orthodontic brackets: An in vitro comparative study. Int Orthod. 2023 Jun;21(2):100751.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37003059\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37003059\/<\/a><\/li><li>Moras CG, Acharya SR, et al. Regenerative biomineralization potential of commercially available remineralizing agents as a preventive treatment approach for tooth erosion &#8211; An in vitro laser-induced breakdown spectroscopy analysis. J Conserv Dent. 2023 Mar-Apr;26(2):165-169\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37205890\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37205890\/<\/a><\/li><li>Jablonski-Momeni A, Korbmacher-Steiner H, et al. Randomised in situ clinical trial investigating self-assembling peptide matrix P11-4 in the prevention of artificial caries lesions. Sci Rep. 2019 Jan 22;9(1):269.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30670760\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30670760\/<\/a><\/li><li>Schlee M, Rathe F, et al. Self-assembling peptide matrix for treatment of dentin hypersensitivity: A randomized controlled clinical trial. J Periodontol. 2018 Jun;89(6):653-660.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29520816\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29520816\/<\/a><\/li><li>Ardu S, Varatharaju V, et al. Protection Against Discolouration by Two Over-the Counter Desensitising Products. Oral Health Prev Dent. 2018;16(5):439-444.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30460357\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30460357\/<\/a><\/li><li>Soares R, De Ataide IN, et al. Assessment of Enamel Remineralisation After Treatment with Four Different Remineralising Agents: A Scanning Electron Microscopy (SEM) Study. J Clin Diagn Res. 2017 Apr;11(4):ZC136-ZC141.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28571281\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28571281\/<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0337765 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0337765\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5f3788a\" data-id=\"5f3788a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4f4e182 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"4f4e182\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47c3aca elementor-widget elementor-widget-heading\" data-id=\"47c3aca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">CURODONT REPAIR &amp; CURODONT PROTECT<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-15bd8e3 elementor-widget elementor-widget-text-editor\" data-id=\"15bd8e3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Godenzi D, Bommer C, et al. Remineralizing potential of the biomimetic P11-4 self-assembling peptide on noncavitated caries lesions: A retrospective cohort study evaluating semistandardized before-and-after radiographs. J Am Dent Assoc. 2023 Oct;154(10):885-896.e9.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37642611\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37642611\/<\/a><\/li><li>Magalh\u00e3es GAP, Fraga MAA, et al. Effect of a Self-Assembly Peptide on Surface Roughness and Hardness of Bleached Enamel. J Funct Biomater. 2022 Jun 13;13(2):79.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35735934\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35735934\/<\/a><\/li><li>Doberdoli D, Bommer C, et al. Randomized Clinical Trial investigating Self-Assembling Peptide P11-4 for Treatment of Early Occlusal Caries. Sci Rep. 2020;10:4195.\u00a0 <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32144336\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32144336\/<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3d7d85c literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3d7d85c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-19897b3\" data-id=\"19897b3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dfdad9f elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"dfdad9f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-67de754 elementor-widget elementor-widget-heading\" data-id=\"67de754\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">WHITENING WITH vVARDIS TECHNOLOGY<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-92d8945 elementor-widget elementor-widget-text-editor\" data-id=\"92d8945\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Bommer C, Flessa HP, et al. Hydroxyapatite and Self-Assembling Peptide Matrix for Non-Oxidizing Tooth Whitening. J Clin Dent. 2018 Jun;29(2):57-63.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30211992\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30211992\/\u00a0<\/a><\/li><li>Hojabri N, Kaisarly D, et al. Adhesion and whitening effects of P11-4 self-assembling peptide and HAP suspension on bovine enamel. Clin Oral Investig. 2021 May;25(5):3237-3247.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33108484\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33108484\/<\/a><\/li><li>Hojabri N, Kunzelmann KH. Adhesion and whitening efficacy of P11-4 self-assembling peptide and HAP suspension after using NaOCl as a pre-treatment agent. BMC Oral Health. 2022 Mar 4;22(1):59.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35246089\/\" target=\"_blank\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/35246089\/<\/a><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8ba0b57 literature elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8ba0b57\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f712b9c\" data-id=\"f712b9c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-96932dd elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"96932dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a9bcef9 elementor-widget elementor-widget-heading\" data-id=\"a9bcef9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">ABSTRACTS,  POSTERS &amp; PAPER PRESENTATIONS<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c2a6a0 elementor-widget elementor-widget-text-editor\" data-id=\"3c2a6a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol>\n<li>Doberdoli D, Haliti F, Begzati A. Efficacy of Self-assembling Peptide P11-4 with Fluoride Varnish or Self-assembling Peptide Matrix for the Treatment of Early Occlusal Carious Lesions. IADR\/AADR\/CADR General Session 2019, Presentation 0368, Vancouver, Canada<\/li>\n<li>Davies RPW, Howard R, et al. Treatment of Fabricated Caries Lesions; Self-Assembling Peptides vs Fluoride. Abstract 143. Caries Res 2015;49:359<\/li>\n<li>Takahashi F, Kurokawa H, et al. Evaluation of Application of Peptide P11-4 on Remineralization of Enamel. AADR\/CADR Annual Meeting, Abstract 1804, 2016, Los Angeles, USA.<\/li>\n<li>Takahashi F, Suda S, Sai K, Kurokawa H, Hinoura K, Miyazaki M. Application of the Self-assembling Peptide P11-4 on Acid Erosion Prevention. IADR\/AADR\/CADR General Session 2017, Presentation 0375, San Francisco, USA<\/li>\n<li>Patel S, Vinh A, Brubaker L, Solomon E, Amaechi B, Noureldin A. In Vitro Assessment of a Novel Biomimetic-Regeneration of Early Caries Lesions. AADR\/CADR Annual Meeting 2016, Presentation 1808, Los Angeles, USA.<\/li>\n<li>Brubaker L, Vinh A, Patel S, Solomon E, Amaechi B, Noureldin A. Remineralization of Early-Enamel Lesions Using Biomimetic Regeneration Combined With Fluoride-toothpaste\u201d AADR\/CADR Annual Meeting 2016, Abstract 1809, Los Angeles, USA.<\/li>\n<li>Godenzi D. Give Teeth a Chance: Curodont Repair in daily practice. Lecture at EAPD, Lugano, Switzerland 2018<\/li><li>Brigi C. In vitro measurement of dental remineralisation: investigating a biomimetic self-assembling peptide treatment strategy. Master Thesis, Queen Mary, University of London, 2014<\/li>\n<li>Burke JL. In situ engineering of skeletal tissues using self-assembled biomimetic scaffolds. PhD Thesis, University of Leeds, Leeds Dental Institute, 2011<\/li>\n<\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Letteratura Table of Contents CURODONT\u2122 REPAIR (A) Reviews Keeper JH et al. Systematic review and meta-analysis on the effect of self-assembling peptide P11-4 on arrest, cavitation, and progression of initial caries lesions. J Am Dent Assoc. 2023 Jul;154(7):580-591.&nbsp;https:\/\/pubmed.ncbi.nlm.nih.gov\/37245138\/ Alkilzy M, et al. Biomimetic Enamel Regeneration Using Self-Assembling Peptide P11-4. Biomimetics (Basel). 2023 Jul 4;8(3):290.&nbsp;https:\/\/pubmed.ncbi.nlm.nih.gov\/37504178\/ B [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-7473","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Letteratura - vVARDIS Switzerland - Biomimetic Dental Science<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/professional.vvardis.com\/it\/letteratura\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Letteratura - vVARDIS Switzerland - Biomimetic Dental Science\" \/>\n<meta property=\"og:description\" content=\"Letteratura Table of Contents CURODONT\u2122 REPAIR (A) Reviews Keeper JH et al. Systematic review and meta-analysis on the effect of self-assembling peptide P11-4 on arrest, cavitation, and progression of initial caries lesions. J Am Dent Assoc. 2023 Jul;154(7):580-591.&nbsp;https:\/\/pubmed.ncbi.nlm.nih.gov\/37245138\/ Alkilzy M, et al. Biomimetic Enamel Regeneration Using Self-Assembling Peptide P11-4. 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